Will you play only at home with friends?
Do you prefer actually playing the game or building new decks yourself?
No, I'd like to play also with other people at the local game store.
There're different Magic formats. They're largely defined by what cards can be used in a deck and how many cards are used. Start by asking what format is played at your LGS.
Do you want your cards to remain valuable and playable after two years?
Yes, I'd like my cards to remain playable forever.
Nope, they never heard of it. — There're other options...