460 S&W out of a rifle barrel

460 S&W is a beast out of a rifle length barrel. It's about on par with 450 Marlin and 45-70 "Magnum" loads. Buffalo Bore makes a 360gr round for the 460 S&W that does 2,300 fps and 4,200 ft/lb of energy out of a rifle length barrel. That's good enough to wreck havoc on any animal in North America.

But, as /u/hearnoweevil said.. the 460 S&W is kind of overkill on a deer. Now, you have the added benefit that you can shoot 454 Casull and 45 Colt out of it. But if you want to deer hunt with a 460 S&W you'd probably want to shoot slower, heavier bullets built for penetration. From what I've read the lighter, faster 460 S&W bullets out of a rifle length barrel will do a lot of meat damage to a deer.

/r/guns Thread