My spouse's parents still live in the house they grew up in. In fact, they designed and built the house before my spouse was born, so their family has been the only inhabitants.

For a long time, my spouse was so upset about the idea of other people living there that we talked inheriting the home someday and staying in it ourselves. We no longer plan to do so because we have our own home now that we like better.

I just asked my spouse this question and the answer was: "I might have some emotions about the house being sold, but it would be merely bittersweet and not debilitating. Especially since, if my parents moved, it would make their life better, such as moving into assisted living or a more manageable smaller home."

TL;DR: It makes sense to have a few feelings about a childhood home being sold but I think films that depict a character completely losing their shit over it are usually doing so for drama, and are also usually about a character that is young and doesn't have a lot of life perspective about how sometimes change is necessary.