An off-switch for obesity: An enzyme within the brain controls overeating.

I was prescribed phentermine for about 2 years. I didn't develop an addiction, but I did grow a huge tolerance.

Over the first 6 months I lost about 50lbs, putting me at 190. Still quite overweight for my height. My doctor wasn't allowed to prescribe me a higher dosage because of how controlled the drug is, so he kept me on the same dosage.

I was left either doubling up my daily dose (and running out short for the month), or sticking to the prescribed dose and hoping it all worked out.

I mostly stuck to what was prescribed and plateaud at 190 for the remaining 18 months I was on the medication. Still, I was happy to finally be able to fit into what I consider "human" clothes. No more rubber bands and zip ties to fit regular jeans around my waist.

My doctor got arrested so I ended up going cold turkey, and in about 4 months gained back all the weight, bringing me back to my 'normal' weight of 230~240.

For a while my friend was giving me his adderall, and while it was similar to phentermine, it didn't seem to be as effective in curbing my appetite. I have miserable willpower when a plate of food is put in front of me. I can't stop when I'm full, I have to stop when it's gone. The best diets I've been on were ones that limited options - Liquid fasts are particularly effective, but only effective short term since it isn't sustainable. Still, the limited options and lack of food stimuli make it easy to not care about food. Yet, it all takes is a bowl of rice and it'll ruin the diet long term unless I can convince myself to stop eating solid food again. I have to be very loyal to liquids only. (3 Ensure drinks a day, and a ton of water. Nothing else.)

Much like liquid fasts, stimulants are a short term fix, especially with growing tolerance and inability to continue receiving the dosage. There becomes a point where your doctor (even if he's a pill mill like mine was) will start to worry that you're just an addict since results stopped showing on the scale. Counting calories is a lot more frustrating than just not eating. There's this weird point where I feel much more hungry after eating 1500 calories for the day rather than just cutting it down to 0~600.

Honestly, sometimes I feel like nothing could be as addictive as food, and if I could just completely quit eating permanently it would solve a lot of my issues.

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