The composition of substances used are irrelevant unless monitoring physical effects. Drugs both illicit or pharmaceutical artificially induce reactions that the brain produces naturally. The experience is what impacts you forever. I don't remember any milestones in my past since 12th grade where I was sober. College was an elevation in maturity as well as exposure to the synthetic compounds. Ironic how erosive solvents even crudely combined, a catalyst spurring biochemical mayhem. But from this dyschronogenicy you experience something that leaves you with a sense of traversed dissonance. If resilient enough to recover from the trauma, you feel more in control more grounded. It's what I can only imagine to be a maturity simulator. I've minimised the frequency of my "induced vacations". I fit in very well socially, however this cumulates in a compulsive need to isolate myself for small periods. I cherish this time alone, seeing it as an opportunity for digestion, defragment and reflect.
This isolation is what allows me to withdraw from social critique. If you break the rules when no one is around to enforce them, is it recognizable as a taboo? Rhetoric aside, growth through malintent implies malevolence. Intent is the key. Intent is the difference between the selfless desire to understand nuance, and the selfish addition of chemically induced euphoria. My point is that for some of us coping methods are raucous enough to be one's degradation. A slow drawn out sacrifice of the self, to be the whole.