Personally speaking, this group is the most stacked for me so far - there are actually a few of my own nominations here (despite them not being my top 3 picks), and I just want to share some characters here that might deserve your vote (including some thoughts for some, but not all of my favorites). Of course, those edits will come from in certain time intervals, so make sure to check back frequently.
Serpico (Berserk): First, I want to say a few words about Serpico. Many of you may know the pillar of manliness that is Guts from Berserk, a character that made it to the second round of the most recent 'Best Guy' contest and is the protagonist of a cult classic. Now, the Berserk anime only had three protagonists - Guts, Griffith and Casca. Fast forward to the part of the manga that hasn't been adapted yet, this guy enters the fray as one of the main characters and one of Gut's new companions. He's the bastard child of a noble who was close to dying in the streets, until a person saved his life - Farnese, another main character of Berserk. This lead to him becoming incredibly loyal to her, even more so once he was told that spoiler He later joins the same order as Farnese and proves to be a skilled combatant, despite his goofy behavior. In fact, despite being skilled with the sword, he is incredibly cunning, and not only managed to fight said pillar of manliness called Guts twice and survived bot times to tell the tale, he even managed to drive him into a corner both times. His loyality to Farnese extends much further than to fighting enemies way out of his league, of course. He later acquires two magical items, a rapier and cloak both infused with Sylphs, elemental spirits of wind, and manages to use the two of them in fairly creative ways to dispatch enemies. In a way, he is the Griffith of Gut's new group - just without being a sociopath.
Saburou (Nobunaga Concerto)
Ozu (Tatami Galaxy)
Maki Ano (Bokurano)
Friend (20th Century Boys)
Fuu Kasumi (Samurai Champloo)
Alice Carroll (Aria)
Kenji Asai (Eden: It's an Endless World)
Reki (Haibane Renmei)
Kenji Endo (20th Century Boys)
Musashi Miyamoto (Vagabond)
Shimura Shinpachi (Gintama)
Benny (Black Lagoon)
Keigo Oonishi (Texhnolyze)
En (Dorohedoro)
Masanosuke Akitsu (Saraiya Gouyo)
Ichise (Texhnolyze)
Asahina Samidare (Hoshi no Samidare)