But, honest question, what are you supposed to do even if you are aware? I have a friend that is severely depressed, severely alcoholic, his apartment reflects that. He's gone to the hospital because of all this 3-4 times this last year, I help as I'm able, I try to be a good friend and listen and offer to help, his family knows he's doing bad, but what else can you really do? Mental Healthcare is not helpful if the person isn't ready to be helped, and a hospital stay is often severely unhelpful, even making things worse if you miss a week of work or lose your job and life gets even harder. A lot of the time even if you pick up on something bring off with someone there's not much you can do.