Dexedrine come in larger capsules than 10 mg because it's by far best stim med i've been prescribed

IMO: Dex IR is a tame Adderall IR. The l-amph in Adderall really gives it that speed feel where as Dex does not have that. It has a smoother effect. In terms of XR - both will deplete and you will feel it, but Dex will pick back up without much fanfare and then Adderall will hit the heart. Vyvanse XR is super smooth in that you do not feel a rush, and you do not feel the depletion, so it'll maintain strong throughout the day.

I think XR serves as base layer. For those that just suffer from ADHD, I think Vyvanse XR is the best medication. If ADHD is coupled with depression or anxiety, or other issues, then I think you need to approach it from a few angles. XR is definitely a strong base but you will also need IR boosters (and benzos) as applicable. Especially coupled with depression, it isn't so much of a happy pill that works as much as it is knowing that the medication is there. If it is entirely smooth, then you start to doubt it, which is why the boosters are helpful to remind you that it is, in fact, working.

/r/Stims Thread