I'm not really prepared to argue for either side of the argument. It's obviously a complex issue since by their very nature, "handicap leagues" are necessarily exclusionary. It's not just women's sports, it's also things like "6ft and under basketball", Little League Baseball, the Special Olympics, etc. All of these activities exclude individuals who are objectively superior performers in favor of creating an opportunity for individuals who have objectively inferior ability to have an opportunity to compete.

The point I am simply making is that if you consider "being against MTF playing in the same league with women" as being "anti-trans", then just about everyone, including staunch trans allies like Destiny, would necessarily be "anti-trans." If you're going to stretch the "anti-trans" label that far, it completely loses all meaning.