This is the best tl;dr I could make, original reduced by 88%. (I'm a bot)

On the brain scans, the researchers found that the women with depression or bipolar disorder had different levels of activity than healthy women in a particular area of the brain called the right posterior parietal cortex.

Under RDoC, NIMH is working with researchers to develop new ways of classifying mental health disorders, independent of the clinical diagnostic codes found in the guidebook that clinicians use, called the Diagnostic and Statistical Manual of Mental Disorders.

The research involved 150 healthy women, 266 women with major depression that was either active or inactive at the time of testing, and 202 women with bipolar disorder who were not in a manic state when tested.

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