That's just a placebo

Not exactly...

"I remembered the number incorrectly but not by much. From the FDA's Orange Book "The FDA requires the bioequivalence of a generic drug to be between 80% and 125% of the innovator product." Now bioequivalence isn't the same as exact dose but if only 80% of that 1mg is actually being absorbed, then why call it 1mg at all? These drugs have to be roughly equal in effects, but they can vary in which enantiomers are included and how the medication is formulated. I can't find the 45% range figure in the new edition of the orange book but another FDA guideline mentions +/-10% in active ingredient alone, not just bioequivalence, and this is in the approval process, not at the production facilities where the conditions are worse. I'm not the only person this has happened to, reports on generic clonazepam's varying effectiveness are not hard to find. Others have submitted complaints to the FDA. In some cases it's as simple as breaking down the pill, which is what my doctor had me do because it was pressed so hard that I wasn't digesting it properly. It helped a little but there was obviously still a gap between what I was taking and what I needed. Mylan was called out by the FDA last year for terrible quality control conditions anyway, and had a recall because of pollutants and dirt visible in pills. No tinfoil hat, but I don't trust the FDA anyways. Sure, they keep literal garbage and rat parts out of our meat and make sure our medicines won't immediately kill us, but they're too intertwined with economic entities when they should be a scientific organization."

Credit to /u/olneyslesion