It sounds like a minor obstruction near one of the fans.
If you haven't blown out the dust in awhile, you might consider getting a can of air, or if your vacuum reverses, blow it out.
Be sure the power is turned off, and the power cord is removed.
Ground yourself by touching something grounded, or wear a ground strap.
Open up the side of the cpu housing that is opposite side of where the motherboard sits.
Blow out the dust, then reverse the steps to return the PC to operation.
If you hear a fan blade click or see it being obstructed while blowing, there's where your problem is. Make a note of which component where the fan is attached, and see if it happens again. You might need to have that part replaced/repaired.
I hope this helps.