None, but i know a lot of people that live their lives constantly questioning whether or not suffering the pain they feel daily is worth it. I know a lot of people that try their best to put on a happy face to appear grateful when deep down they struggle to find a reason to keep living. Sure Joker is a huge exaggeration of this but there's a reason why the movie struck a chord. The people who need compassion the most are the ones kicked to the ground and shit on. And the most egotistical people are the ones everyone in the room listens to. I think that our entire culture is built around the escape of the deep spiritual pain rather than confronting it. Humans are just not very self aware at the moment.