It's perfectly reasonable to be upset about not being able to fulfill your biological purpose due to things out of your control.

To be honest that played a big part in me being depressed when I was younger even getting to the point where I had my Dads rifle on the bed with some ammunition after I finished High School (honestly it probably wouldn't have worked anyway given how old the stuff was). I have a condition that most likely means I'm sterile and am not exactly well endowed due to said condition. In the end I'm glad I did get over said depressed thoughts and never did let myself get pulled into those toxic groups. Overall I just came to accept my shortcomings and become content with my life while having a good career that lets me live the life I want. If I end up finding someone someday great but otherwise I'm not exactly losing sleep over it.