Some things OSBuddy/pro has done, does and is planning to do and some effects:

• OSBuddy mousekeys (when they were accepted) were 1:2, which before the AHK ban was considered to be against the rules
• open gl: increased render distance so much that you were able to walk/run longer distances with less clicks, which made many things, especially rcing, easier and more afk (patched)
• OSBuddy farming helper: gave players exact timing on when farming patches are ready to be harvested, indirectly increased xp rates for OSBuddy users by making it easier to maximize farming efficiency (patched)
• left click use option for bones: indirectly increases xp rates by making 1tick prayer training easier
• sliding puzzle solver: removes one of the key obstacles for monkey madness 1 and high tier clue scrolls (takes away from integrity of game)
• OSBuddy exchange price: allows for merchers to EASILY manipulate the price of items
• open gl in raids: easier to determine if raid should be skipped, giving OSBuddy users an unfair advantage over non users (not patched)
• planned release of OSBuddy clipping: a work around on the AHK ban, everything can be clipped and moved around accordingly to be able to work with WMKs up/down/left/right functions to achieve some of the same results as AHKs

OSBuddy should only be allowed to add overlays and change the colours of text and other things that do not directly impact gameplay. A third party software should not be allowed to change the actual user interface or change the dynamics of the GE or add updates that force Jagex to add a patch to nerf.