Actually, you’re in luck! Mirtazapine is one of the only, if not the only, tricyclic antidepressant that does not block reuptake of that main fun neurotransmitters. So it’s actually a fairly safe drug. I have a bottle of dozen and dozens of them even though I stopped taking it. It’s perfect to kill a roll or a trip. I have also used it to sleep after coke.

That being said, I never do them at the same time. I always always always use it to end a trip, roll, etc. It actually blocks (antagonizes) most of the main transmitters. So it will 100% make your trip, roll, tweak, etc. much less powerful. Maybe even end it completely. If he must take it the same day tell him to take it on the comedown for sleep. I was only on it for sleep not for depression. If you have any other questions lmk. Or use Wikipedia. That’s where I learned all this.