Fwiw, I started the game a few weeks ago and I've been hunting the "money meta" for a couple of weeks now. Imho, the best $/hr is VIP passenger runs from Evans Port (in Parutis) to Vela Dock (in Medb). The guides say to run economy cabins for max passengers, but in my experience you get better $ for VIPs (not luxury, yeah, I made the mistake of trying that). I'm averaging ~75 Mil a run (run takes about an hour with board flips) in my Anaconda but you could just as easily roll with a Python. I was doing Ceos to Atmospherics before (when it was in boom) and that was decent for Fed rank but only netted around $10-12 Mil a run for like a 20-30 minute turn around (including board flips)