Sorry for the novel below. This has been sitting in my mind for the past few months or so.
TL;DR: The potentially abusive relationship he has with his wife.
I'm 31 now and I've known this guy since I was 6. This guy, along with another one of my buddies, have been friends since the first grade. We were inseparable until we all split for different colleges, but kept in touch. Our parents never moved away from my hometown, so we'd visit each other's houses all the time during the holidays or during summer break. We all served as groomsmen at each other's weddings. Simply put, we were all very close lifelong friends.
About 5 years ago he kind of went through a quarter life crisis. He had been unemployed for quite some time and was in a funk, mooching off his parents for food and rent. He ended up meeting this girl...and though I don't know much of the details (I moved the furthest away for college and for work), it turns out that no one (not even the parents) really likes her. She's clingy, kind of manipulative, and well really changed him. He ended up changing his entire personality within the span of a month or so. It's so weird to see the person that I grew up all of a sudden become kind of like a misbehaving puppy on a short leash. It feels like he always has to watch what he says and he does before the gets whacked on the nose.
Everyone thinks she's taking advantage of him...for instance:
They bought a house together, but only his name was listed on the deed. His parents think that this way, she'll walk away with more of his assets once they eventually divorce.
No one can get any alone time with my friend. His girl is ALWAYS with him. His parents can't spend any time alone with him. He was best man at my other friend's wedding and we threw a bachelor party in Vegas. She came along.
They initially got engaged earlier (she was walking around with a ring), but a few months later, the ring disappeared, and a year after that, they announced that they had eloped in Vegas.
His dad is concerned that he keeps mooching money off of him. Apparently he's sold off all of his stock options his dad passed on to him. And he asked for $5000 to help set up his wedding...which brings us to the good part of the story...
A few months ago, he asked me to officiate his wedding, which I obviously agreed to do. About two months before the wedding, they ended up UNINVITING EVERYONE on the groom's side. Apparently they had an altercation with his younger sister and they decided that everyone (without exception) he knew was detrimental to their relationship. So all friends and family (including his parents, who paid for the down payment for the wedding venue!) were cut off from his life. Every last friend and family member, which includes cousins, aunts, uncles has not talked to him since the un-invitation. In fact, most of the friends didn't even get a good explanation. They were just told that the wedding had been cancelled.
The groomsmen (and the officiant). all of us friends since grade school, received a phone call from him (but secretly we were on speaker with his wife as well...the whole time baiting us to say something terrible about her), effectively ending our friendship. And that's the last time I've ever talked to him.
He also owes me $40 bucks. I had to pay $40 for a deposit on the tuxedo rental. I go out and reserve my tuxedo early and he goes and uninvites me to the wedding? Bastard.