3. Prions, abnormally folded proteins that can spread in the brain, remain a scient...

Prions, abnormally folded proteins that can spread in the brain, remain a scientific riddle. They appear to be a key factor in Parkinson’s, Creutzfeldt-Jakob, Alzheimer’s. A copper-induced folding problem, together with a tendency to clump together, could be the culprit at the molecular level.

I disagree with how this is worded. It has been known for quite some time that amyloid-beta and tau are malfunctioning proteins that appear in the pathology of neurodegenerative diseases. A-beta plaques and neurofibrillary tangles (abnormal tau pathology) are hallmarks of Alzheimer's and are also seen in Parkinson's. Although the proteins accumulate and spread throughout the brain as these diseases progress, the pathology is not transmittable between organisms. If you have AD and someone eats your brain, they will not get AD. Will they get a prion disease? Maybe. The point is, that is likely a problem separate from the amyloid and tau. There is a connection between these diseases - it is malfunctioning proteins. I would not consider prions to be a 'key factor' in AD and PD. CJD is a prion disease itself, so the misfolded proteins would obviously be a 'key factor' in that disease. I am not claiming to be an expert on this, but I've done a fair amount of research involving AD and I think this is a little bit off. This article isn't, in my opinion, a sound interpretation of the paper it is describing. The paper only mentions Alzheimer's twice - once in the intro and once later on. Both regarded general attributes of the disease, not direct links to prions. tl;dr imo this isn't a good article, is meant to be sensational with little weight behind the connections it makes

/r/science Thread Link - laboratoryequipment.com
Previous
Next

Recently removed from /r/science

As a four-day work week is trialed in countries across the globe, health researchers say they’re ‘all in’ when it comes to a long weekend, research shows that the extra time off is good for our health. Findings from a study of more than 46,000 people from 68 different countries reveal those who share more left-wing political views are more generous and altruistic than those who follow right-wing ideologies. Obesity might adversely affect social and emotional development of children, study finds Decline in daily step count persists after pandemic for U.S. adults. Based on new findings, people had not yet bounced back as of December 2021: U.S. adults were still taking around 700 fewer steps per day, compared to their pre-pandemic norm. Review of 1,039 studies indicates exercise can be more effective than counselling or medication for depression Researchers are calling for exercise to be a mainstay approach for managing depression as a new study shows that physical activity is 1.5 times more effective than counselling or the leading medications One theory of attractiveness suggests beautiful people are seen positively and these views become internalized, motivating altruistic behavior. New research, however, finds support for the view that beautiful people behave selfishly and feel entitled due to their bargaining power in relationships. Extremely rich people are not extremely smart. Study in Sweden finds income is related to intelligence up to about the 90th percentile in income. Above that level, differences in income are not related to cognitive ability. ACPeds Calls on Organizations to Scrap Current Transgender Protocols Based on Newly Published Critique Most Americans aren’t getting enough exercise. People living in rural areas were even less likely to get enough exercise: Only 16% of people outside cities met benchmarks for aerobic and muscle-strengthening activities, compared with 28% in large metropolitan cities areas. Magnetic solution removes toxic "forever chemicals" from water in seconds Neighborhoods with predominantly White residents have more greenery, fewer dilapidated buildings and fewer multi-family homes — compared to neighborhoods with residents of multiple races and ethnicities, predominantly Black residents Routine vaccinations drop among U.S. kindergartners for the third year in a row according to the CDC. While vaccinations remain high, coverage has dropped from 95% in the 2019-2020 school year to 94% in 2020-2021 to 93% in 2021-2022, leaving at least 250,000 potentially unprotected against measles. Clitoral knowledge and gendered sexual scripts appear to play a key role in women's orgasm experience Clitoral knowledge and gendered sexual scripts appear to play a key role in women's orgasm experience

More Random Comments

Metonymy is a self-defense mechanism I feel alone because I basically hate the trans community Please HELP- my son is a Narcissist. How do I help him stop. Oculus VR is funding about two dozen Rift-exclusive games Tumblr user racist for hating the word "Extra" DONE: Schweinsteiger joins ManUtd from Bayern, according to Bild The Federal Government runs the Compassionate Investigational New Drug program; there are currently four surviving patients who receive 4 - 9 ounces of cannabis per month from the Federal Government through the University of Mississippi; the program does not accept new patients Test, please ignore Noise in the coax lines, old TV blamed as culprit, plausible? (xpost from /r/techsupport) An old team at reddit DONE: Schweinsteiger joins ManUtd from Bayern, according to Bild An old team at reddit What [SERIOUS] Work-At-Home jobs i can take nowadays? You always hear of girls...But guys of reddit who have experimented with a same sex friend. How'd it go? Did it become awkward? What is something rich people buy that poor people know nothing about?