First of all, know the general pipeline for the ngs data processing. If you are comfortable with it, awesome! Then try to see what others at the company are working on right now. Their website might give you a general idea on what they work on but "stalk" the employees LinkedIn to find the technologies and tools these use for the said research goals.

The final nail in the coffin would be to equip yourself with the knowledge of what's happening righ now. Go through some of the latest Nature Genetics, Nature genetics review and other good journals regarding the said research topic.

With all this knowledge, you will not only be able to answer all the technical questions but also be confident during the whole process.

Lmk if this helps!