Well the starting dose is 25mg then Dr doses it up as your body gets used to it. Maybe it was too high of a dose for it to be tolerable. I never heard of this substance being used in combination to make other things stronger. It's used in low and safe doses to cut the high from a stimulant so that one can sleep. I made the mistake to take an entire 100 something MG of Seroquel not knowing any better. The following day was awful! I couldn't articulate my words and I took my script of dexedrine with it. It was the worst day of my life. And I had to be with the family for Thanksgiving dinner while all along, I was trying to figure out which best way should a fork be held. And in front of a family in silence. Never again! Please be careful.