Seroquel and MDMA

Sorry I'm super late to the game here. I came across this on Google and hope someone can find my experience useful.

As I'm sure OP has found out, you will roll just fine even 24 hours after a single low dose of Seroquel. The half life of IR Seroquel is 6 hours so a single dose is in and out pretty quickly.

After trying virtually every other anti-psychotic, I've been on Seroquel for the last year and a half from 200 to 400 and now 600mg. I suffered from frequent, severe manic episodes and Seroquel has been a God-send. I'm stable, fall asleep easy and stay asleep. I've held the same job for a year, prior to that, I'd never last more than 3 or 4 months. Seroquel is heavy duty shit. Unless you have a legitimate medical need for it and nothing else has worked to treat mania, I'd avoid it at all costs.

All that said, Seroquel has seemingly more or less ruined MDMA for me. I've had straight to dark purple pills and molly over the last six months and it was extremely annoying. My friends all got completely buttered. My pupils saucered and I felt kind of speedy and fuzzy but nothing like when I rolled before taking Seroquel. The same also appears to be the case with LSD and mushrooms. Some mild effects while my friends are annihilated.

While I wouldn't recommend using any kind of psychoactive illicit substance (aside from weed) while taking Seroquel, I've found a cannabis and Adderall combo still works quite well. 3 15mg XR while puffing quality Sativa dominant flower or clean dabs/wax with similar genetics, every couple of hours is my sweet spot. It works every time, gets and keeps me bent basically as long as I want it to.

/r/Drugs Thread