possibly supplement it with a low dose (maybe 2mg) estradiol if I start to feel too crappy on just the AA alone It should be fine although I would advice against taking the Estradiol tablets orally due to their low bioavailability via that method. You should do Buccal Administrartion. You should not do buccal/sublingual administration if you are going to buy Estradiol Valerate tablets like Progynova as the EV is weaker in its tablet form in comparison to other estradiol formulations unless it is digested. The pills that you want for buccal administration are Estradiol Hemihydrate (Elleste Solo,Estrofem) and 17-b Estradiol tablets (Estrace,Mylan). It is advisable to do BID(twice a day)to TID (thrice a day) dosing of estradiol if it is taken buccally due to the 8-18 hour half life.