I'll just say that I find your answer flippant, and in poor taste. With all due respect and gratitude for your work, etc.

What happened to Alan Turing was terrible - basically his life was ruined in all kinds of ways by those who persecuted him. We should not speculate about what exactly pushed him over the edge.

I was also not suggesting keeping someone on "inappropriate" HRT for more than a few days. The idea I presented is more akin to testing of psychopharmaceutical drugs, or, closer yet, trials of psychedelics in clinical psychology.

Giving people magic mushrooms can also make the test subject feel pretty out of sorts for a time, but we still do it, because there is benefit in learning about what these drugs do to a person's mental state.