As for any news (especially game-changing like this one), until it is independently verified everything must be taken with a grain of salt.
There is only one source for the claim which is Azov & it's in Mariupol where the situation is the absolute worst making it very difficult to get info & verification from another party.
What we know as of right now that plays in favor of the claim:
- Newly assigned general, Dvornikov 2 days ago, known for brutal tactics & using chemical weapons in Syria
- Head of DPR, Basurin, mention idea to use chemical weapons in Mariupol on Russian TV prior to the attack
Note: BackandAlive claims the poison used was Sarin.
Reminder: Polish President said if Russia use chemical weapons it would be "game changer", therefore a more vigorous investigation will be made before any official confirmation.