I personally will heavily replay games like Arkham LCG to try out different builds, branching paths, etc. That said, most of my group are 'experience gamers' in this regard so once they've seen a narrative a time or two they're done. This makes certain games a hard sell because my motivation to buy-in takes a serious knock unless I want to spend the entire replay cycle playing solo or finding different groups.

In the case of Arkham I gave up on the LCG and went with 3rd edition. It scratches the Arkham itch, features it's own flavor of the 'opaque container of self loathing', has six scenarios to explore (with Dead of Night) and at the end of the day cost me about $65 total instead of $500+.

Different types of games out there in this space though, so it all depends. Games like Time Stories or Pandemic Legacy are by design more of a consumable product.

Know your audience prior to purchase, I suppose. And factor in solo play, if that exists for you.