What time of day should I try codeine and tramadol (if first time)?

Well, you've hit the nail on the head really, I wanted to know if you need to factor in when you stop feeling the effects in order to sleep or whether it's not necessary!

Quite, SNRI action is something that's often said in relation to tramadol but I've not read any studies on its severity or if it's really relevant at all.

No, I've tried virtually every other class of recreational drug under the sun but never opiates, I was heavily into the RC scene but opiates weren't featured (at least in the UK). U-47700 I'd heard about but mixed reviews and I didn't want to jump in with something that heavy when trying opiates, hence DHC and tramadol seemed a good place to get my feet wet.

I've been a sucker for benzos in the past, particularly the powerful RC ones that were around (clonazolam, flubromazolam in particular). Do you think someone who likes benzos will likely see the appeal in opioids? I'm not really sure which answer I want to be given to that question actually haha.

These days I'd rather keep my benzos for recovery and treating myself, my anxiety is virtually all-gone (or at least at healthy levels) these days so I don't have to walk the metaphorical tightrope that was being able to use it therapeutically versus going on a month long benzo haze rampage (facilitated by those insane RC benzos).

/r/Drugs Thread Parent