Heather Alexandra had a great piece on this.
The main concern stems from how Bethesda has marketed this game as featuring things iconic to the franchise, like Vaults, T-series power armor, and nuclear weapons, and treating them as accessories to the world and fun things players can interact with, instead of how they were originally depicted as in the original games: signs of America’s disturbing nationalism, exceptionalism, and jingoism that led to the world being utterly devastated.
I’ve come to accept that Bethesda wants Fallout to go in an entirely different direction than the original writers did, but I don’t think this is a healthy direction for the series. They’re looking at the elements previous Fallout games gave harsh criticism to, and thinking, “whoa, cool robot”.
Fallout 4 had a similarly genuine nostalgia for the old world that was quite disturbing, given the reality of the old world was the US annexing Canada and executing their civilians in the streets.