Assuming this is a legit question:
Her hawkishness. Hillary supported every single war in her lifetime (including Vietnam[!?!?!]) and actively pushed the WH to engage more countries (ie. Libya). She voted Yes on the AUMF and defended the Iraq invasion long after most Ds admitted it was a horrible boondoggle.
Her cozy relationship with banking/financial institutions. Goes without saying, but giving high paid speeches, which she refuses to release, to banking interests seems a lot like buying favor. The Clinton Foundation connections are also quite uncomfortable - foreign nations 'donating' support to the organization that pays Hillary Clinton while she's SoS and approving arms deals / sale of uranium mines?
Refusal to support same sex marriage until AFTER Obama flipped. You simply can't have opposed gay marriage until 2013 - that's the wrong side of history and it's unforgivable. The only outcomes I can accept are that she either really does oppose it, or she supports it but is too cowardly to defend a position that isn't guaranteed to be popular.