Full 1LLL is ~3900 algs..

The issue with the edges being misoriented is that which edges are misoriented becomes a problem. Even if two cases have the identical corner orientations and corner/edge permutations, you'd still need completely different algs with completely different recognitions. It's like the difference between COLL and OLLCP. Both functionally do the same thing (solve everything up to EPLL), except that COLL is a much reduced set because edges are already oriented (40 algs vs >300).

You also have to consider your lookahead during F2L. Judging and solving EO during F2L is comparatively easy, but forcing a specific OLL case is much harder. So, even if you learned the full 1LLL set for OLL case 14 (for example), you probably wouldn't be able to force that specific case often enough to justify learning all the algs.

You may be able to get away with doing partial edge control (during F2L) and then doing something like phasing (from ZZ-b) to force your EOLL to be a line every time, but that would still leave you with 14 OLL cases to learn the 1LLL algs for. To me, this seems like it would be objectively worse than just doing full EO during F2L (VHLS, anyone?) and regular ZBLL, which is a 1LLL set from only 7 possible (corners only) OLL cases.