There's this:

SR 2 [IN THE SOUTHERN CALIFORNIA AREA] IS CLOSED FROM 14 MI EAST OF LA CANADA TO 18.1 MI EAST OF LA CANADA (LOS ANGELES CO) - DUE TO SLIDE REMOVAL - MOTORISTS ARE ADVISED TO USE AN ALTERNATE ROUTE

ALL TRACTOR-SEMI TRAILER COMBINATIONS WITH 3 AXLES OR GREATER ARE 

PROHIBITED FROM THE JCT OF I 210 /IN LA CANADA-FLINTRIDGE/ TO THE ANGELES FOREST HIGHWAY (LOS ANGELES CO) - ALTERNATE ROUTES ARE AVAILABLE

http://www1.dot.ca.gov/hq/roadinfo/Hourly

I believe this means you should be able to approach from the East, though. Someone on IG the other day posted they were at Big Horn Mines and were able to drive right to Vincent's Gap. As a former Wrightwoodian, I would have driven up Hwy 2, past Big Pines to get there. We called coming in from the West "The Back Way". So, go the front way, out 10>15, etc.