According to this: https://www.reddit.com/r/linux_gaming/comments/gjzkzk/comment/fqo2ykm/?utm_source=share&utm_medium=web2x&context=3

So, no. Wine CAN'T run kernel level anti-cheat. You're just fear mongering.

Also, read this. https://www.altchar.com/game-news/is-genshin-impact-safe-to-install-on-your-device-and-other-security-questions-aQ0659O50hzV

Why people still scared of Genshin, boggles my mind. Some are just genuinely concerned, some or just anti Chinese racist people.

Well, at the end it's your choice to play or not. Genshin is as invasive as rainbow six siege, Valorant, and Fortnight, so if you think any of this game's anti cheat, is still within the limits, then Genshin, is probably fine. For me, these types of game is a bit too invasive, so no thanks.