Solution to the issue
It ended up with my gamefiles being corrupt and needed to download a new client. But before resolving to that, there was a serial of steps there should be tried first.
Note: There are several files you need to make sure are covered by these rules. Client.exe, PathOfExile.exe, and CrashUpload.exe. All found in your game folder.
If that does not work, then move on to trying to fix the files manual.
When I did it, it kept sending me a new error, with a different number. After a bunch of different numbers, it returned to the first one and started over. At this point I was told that my gamefiles has been corrupted and needed a new install.
I hope this can help someone else, if they happen to get the same error. Furthermore, do not hesitate contacting support at [email protected]. I wrote to them a late Saturday evening (CET) and got a reply within 30 mins. Each following mail in the troubleshooting where less than 20 mins between. They react really fast and provide good solid, accurate support.
Personal I'm more tempted to invest in a supporter pack, after this experience.