Been playing Blessed Matheo in Innsmouth conspiracy, and this amazing turn happened. By using Favor of the sun and that card that lets you turn two blesses into elder sign, some lucky token draw, and some other cards I do not remember, I managed to trigger Matheo's Elder sign ability 4 times during single turn. The whole table was losing their minds.
I remember that this happened second time in that campaign, this deck was built around that, but when it happened first time, it was such amazing and hilarious experience.
That was the scenario where you escape from Innsmouth, and it quickly went from "okay, I'll probably be caught by the wave" into "cool, we're owning scenario" during that turn.