From the source https://getibogaine.com/ Ibogaine, or ibogaine hydrochloride, is the name of the principle and best-researched active compound in iboga. It can appear as off-white crystals or in the form of a clear solution. Doses of about 15-20 mg/kg (so as high as 1400 mg for a 150 lb individual) are typical for addiction treatment. Many treatment centers have had excellent results with it, especially with opiate addiction as it can completely eliminate withdrawal. It has been extracted and synthesized with 95-99% purity, so the dose can be very carefully controlled and calibrated to suit your specific needs.

Ibogaine passes through your system more quickly, in about 14-24 hours, leaving less of an “afterglow” than iboga. This also means that it has a shorter recovery period, which is more in line with what some individuals need. Pure ibogaine tends to lead to more hyperactivity afterward, whereas iboga results in a more balanced state.

Ibogaine is only one of eleven or more compounds found in the various iboga species. Some, like tabernanthine, have good research showing that they have similar active properties to ibogaine, but others are still being studied. For some, this is a good argument for pure ibogaine — you know exactly what you’re getting. Our bodies also metabolize ibogaine into noribogaine, a metabolite produced in the liver, which may be responsible for some therapeutic effects. On the other hand, the true therapeutic value of iboga could come from another chemical, or even interactions between multiple chemicals, which is the case for ayahuasca. The traditional benefits of iboga may be lost along with the hundreds or thousands of additional compounds you may be missing out on.