None of this is atypical kitten behavior. NeglectedOrCrazy's suggestion to watch My Cat From Hell is great. There is a lot of helpful advice on that show. *1. Redirect the kitten's attention. Right now he is biting feet, ankles, or whatever is in front of him. Little kitten teeth and claws are sharp, and they have no concept of "play biting." It's important to stop him in the moment and direct that biting/clawing to a toy. Don't swat him or physically punish him for clawing at you, as that will only teach him aggression. I had a similar kitten and I would wear him out with a laser pointer and feather toy. He also had his own stuffed animal to beat up and a scratching post to test his little claws on. *2. Be very mindful of cables. I fostered a kitten who bit into a power cord and literally blew the roof of his mouth up. It wasn't pretty or cheap, and he barely survived after the wound became infected. I became very mindful of exposed cables and kept them out of reach or blocked as much as possible. He is 3 now and I have caught him chewing on my laptop charger since. It is still kind of an ongoing battle. *3. Let me know when you figure out how to stop this. :) *4. Let the Siamese kick his butt a few times. He needs to learn boundaries, and that he is not he alpha. Maybe he will learn to leave her alone. Obviously, don't let her really hurt him, but I wouldn't rush to break them up. *5. Wear him out with a laser pointer before you go to bed. If he starts up with the meowing, try putting him on your chest in bed. My cat (the one who blew himself up) did the same thing and I would put him on my chest and pet him for a little while until he fell asleep. Your sleep is important though, so if you have to put him in a crate in the bathroom, don't feel bad. He will grow out of it. *Lastly, is he old enough to be neutered or has he already been neutered? My cat's nocturnal madness mostly stopped after being neutered. *Source: Fostered 20+ cats and had a kitten very similar