I have already said it. He overwhelms their ability. The soullessness/null field are the same, you can't have one without the other. And that can be overwhelmed by a strong enough psyker or warp based creature. Why is this so hard for you? A sister's null field/soullessness can overwhelm a psyker or warp based creature so why can't the opposite be true?

Beyond that, we know from The Thousand Sons book there are five schools of psyker discipline using the warp:

Biomancy: Manipulation of biological energy and processes Divination: Predicting the future Pyromancy: Manipulation of fire Telekinesis: Converting psychic energy into physical force Telepathy: Contacting and controlling the minds of others

The Emperor telepathically communicates and 'shows' himself over and over to people based on their preconceived notions of what or who he is. He manipulates their mind. There soul or lack of soul has zero to do with it because he has already completely overwhelmed their ability to stop him. He was literally so powerful that the gods of chaos, who are forever at war, had to stop that war and team up to try to stop him. Yet some rando sister is powerful enough to check him? It is easy to not doubt when the argument lacks logic.