Well, the weekend usually starts with Friday. Then, after Friday comes Saturday. Saturday is the middle of the weekend for many people. After Saturday comes Sunday which is the last day of the weekend and is affectionately referred to as "Sunday Funday" by some people.
That's the general idea of what a weekend entails.
However, if you're looking for suggestions of fun things to do, I would suggest a few of the following which I find to be of great enjoyment.
Or, you know.. you could tell us some shit about yourself and your woman. What you like, what you don't like, the neighbourhoods you are interested in, what you're looking to do, how much you want to spend, how old you are, what type of crowd. Oh, you know. The basics.
OR CHECK THE FUCKING SIDEBAR LIKE A RESPONSIBLE PERSON.
This shit gets asked every other day, and everyone expects brilliant answers to "Hey, what can I do in the city this weekend".