Absolutely. This is an opinion piece and should be taken as such. But isn't that what you're responding to? This opinion piece?
Your response just seems so odd in that you claim he is acting guilty because he isn't a sociopath. This is odd because:
I'm not even necessarily that far away from what I presume is your opinion: That this isn't good evidence of guilt. But I feel the reasons I provided (he always acts defensive even against baseless accusations) are a little bit more on key than suggesting that his feeling guilty is a sign of him not being a sociopath. Your saying its a good sign that he is acting guilty about getting accused of colluding with Russia because it shows strong moral character to be able to feel guilty? That standpoint kinda throws him under the bus instead of making the point it seems like you're trying to make.