England here. Here are some of my observations, bear in mind they are very opinion based however I've lived for a long time in both the north and south and here is what i saw:

The north is more commonly under educated and under funded, a lot more based around antiquated industry and family. The accents are much harsher due to slang terms used within industry and from the massive influx in foreign workers/migrants during the time the ports where in use, also people are much less likely to move away from home and therefore each generation the accents become more 'condensed'. Classically the populations in the north favour a more liberal government that favours the working class, however in recent years there has been a large influx of business to the large cities of the North, creating more jobs and great opportunities. People are generally friendly, happy to help, superstitious, proud of their birthplace, more family focussed than career focussed.

The South (closer to London the more true) is typically less centred around industry and now becoming saturated with tertiary industry and wealthy commuter towns. London is the hub of the South with most young professionals gravitating towards the capital, and from personal experience families are more likely to be spread across cities in search for better work. The accents are less distinguishable to that of the north (until you travel west past the centre of the country, where you get something similar to the North) probably due to a lot of moving around and wealthier neighbourhoods with less lower working class slang and colloquialisms. People are generally fast paced workers, well educated, less rooted to their birthplace, slightly less community oriented, outgoing.

Sorry Midlands.