3. Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoiet...

Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoietic Diseases, Chronic Inflammatory Diseases, and Cancers

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Profiling of length heteroplasmies in the human mitochondrial DNA control regions from blood cells in the Korean population. Electrophoresis 2006;27:1331–1340.9.Gattermann N. From sideroblastic anemia to the role of mitochondrial DNA mutations in myelodysplastic syndromes. Leuk Res 2000;24:141–151.10.Ergen AV, Goodell MA. Mechanisms of hematopoietic stem cell aging. Exp Gerontol 2010;45:286–290.11.Park CB, Larsson NG. Mitochondrial DNA mutations in disease and aging. J Cell Biol 2011;193:809–818.12.Shin MG, Kajigaya S, McCoy JP Jr, Levin BC, Young NS. Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrow. Blood 2004;103:553–561.13.Liu Y, Long J, Liu J. Mitochondrial free radical theory of aging: Who moved my premise?. Geriatr Gerontol Int. 2014doi: 10.1111/ggi.12296 [Epub ahead of print]14.Stuart JA, Maddalena LA, Merilovich M, Robb EL. A midlife crisis for the mitochondrial free radical theory of aging. 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AbstractArticlePDFPubReaderePubFigures + TablesReferencesMeSH Terms:

Adenosine TriphosphateAgingBone MarrowChronic DiseaseDNA, MitochondrialGenome, MitochondrialHematologic NeoplasmsHematopoietic Stem CellsHistonesInflammationIntronsMitochondriaOrganellesOxidative StressReactive Oxygen SpeciesSubstances:

Adenosine TriphosphateDNA, MitochondrialHistonesReactive Oxygen SpeciesSupplementary Concepts:

Bone Marrow failure syndromesFigures:

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National Research Foundation of Korea2011-00153042010-00243262011-0030034Ministry of Health and Welfare2013-1320070

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