Well the workplace alienation thing is just capitalism, everyone feels that. To alleviate that feeling, I recommend either joining your local labour union or agitating for worldwide socialist revolution.

With that said, /r/askphilosophy is not that good of a place to be getting life advice from. If you really do feel empty and depressed, a good psychiatrist or mental health professional can help.

Personally though, my advice to you would be the same as what Frank Ramsey would've said, responding to people who felt that their lives were insignificant because of our smallness as human beings in the grand scheme of the universe.

My picture of the world is drawn in perspective, and not like a model to scale. The foreground is occupied by human beings and the stars are all as small as threepenny bits. I don’t really believe in astronomy, except as a complicated description of part of the course of human and possibly of animal sensation. I apply my perspective not merely to space but also to time. In time the world will cool and everything will die; but that is a long time off still, and its present value at compound discount is almost nothing. Nor is the present less valuable because the future will be blank. Humanity, which fills the foreground of my picture, I find interesting and on the whole admirable. I find, just now at least, the world a pleasant and exciting place. You may find it depressing; I am sorry for you, and you despise me. But I have reason and you have none; you would only have a reason for despising me if your feeling corresponded to the fact in a way mine didn’t. But neither can correspond to the fact. The fact is not in itself good or bad it is just that it thrills me but depresses you. On the other hand, I pity you with reason, because it is pleasanter to be thrilled than to be depressed, and not merely pleasanter but better for all one’s activities.