Puzzle: Which play ensures my best chance of victory?

In order to get a kill, you'd need to bypass the Invincible buff the heart has, but the only way to do that would be to use Static Discharge, which you don't have in play. (The lightning icon is Electrodynamics.)

So the plan is to block this turn. Highest block you can get is Leap+, Leap, Charge Battery+, and Defend+ (also Leap+, Hologram+, Leap+, Charge Battery+), for 39 total, counting Smooth Stone and after Beat of Death. This will leave you at 2 hp, meaning you can't play the Defend in your hand or else you won't have enough energy for the other block cards, and you'd be losing a minimum of 3 block, which also means you lose 3 hp out of the 2 you have left.

So the play is Reboot+ and pray.

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