I feel like, barring activities that are better enabled by a certain body type (tall people playing basketball, for example) as long as you weren't born with any disabilities, you ought to be more or less tabula rasa and able to pick up whatever skills you desire; it's just my own personal theory, but I feel like these are very much a "nurture" thing. What did we take an interest in? What was encouraged/discouraged? Did your family have enough money or knowledge to enable and speed along your progress? If you grew up in a family with a long line of creative types and you display a propensity for artistic endeavors, it may be partly from having grown up around it and partly because they're more likely to recognize how much joy it brought them and nurture the same in you, provide you with materials and tools, etc. If your dad was a jock and plays catch with you from the time you're able to pick up a ball, you'll probably end up better at sports than the other kids. Not to say that one's own interests apart from your family's can't emerge, but I feel like if there is a seemingly genetic component to it, it's probably due to that environment aspect. Anecdotally, I was the youngest kid by over 10 years and while both of my sisters played instruments, it was never around me (parents split up when I was a baby and my mom took only me.) My parents were musical when they were younger but again, never played around me. My grandmother was a piano teacher before she retired but I didn't find that out until I was a teenager. Music ended up being my passion, but despite my family never playing around me, I was still encouraged and provided for in my musical interest every step of the way. I'd consider us a "musical family" but not because it's in our genes, but because it's something generation after generation of us have put our hearts into and encouraged in our children.