Definitely invest in a tablet that comes with a pen and has handwriting capability, being able to take digital notes and upload them automatically to the cloud, share them with classmates, even audio record lectures (if you're allowed). Annotating readings or course slides is a huge boon as well. Saves a lot of paper too.

I was a big fan of the Squid app on Android tablets personally, so much that I shelled out the buck a month (or so) for the premium version. Pretty fair price. Only gripe is that even though you can easily manually export individual notes and PDFs to Google Drive, you cannot do this en masse automatically (only to Box or Dropbox).