There are other costs that might apply for some classes and not others, but the above apply to basically all of them.
For in-person classes, hypothetically all most of them need is a classroom and seating, and the buildings are all a sunk cost regardless of if classes are online are not. Consequently, it is uniformly more expensive for ISU to offer a class online than offer it in person. This is true for basically all higher ed institutions that already have an in-person campus to start with.