The first time I had an alcoholic beverage was about six months after my 21st birthday. I just hadn't ever seen the point and wasn't really into the idea. The first drink I had was a Strawberry Daiquiri. It tasted like someone pouring rubbing alcohol into a delicious strawberry smoothie, thereby ruining it.

I didn't even bother trying anything else until the following summer when I was studying abroad in Ireland. My house-parents served the other American student and me a glass of red wine on our last night. It was like trying to drink sandpaper. I got through about three sips before just giving up. When we were all out as a group at a pub, I ordered a Bailey's on the rocks which was actually not completely disgusting, just super sweet and creamy. I didn't even try beer in Ireland.

A while after that, I tasted beer for the first time. That was right out. Gross, bitter, vile, etc. Why would anyone want to drink something that tastes like horse piss? No thanks.

I don't remember exactly when it was, but somewhere around my 23rd birthday, I finally tried something that not only didn't require me to "acquire the taste for", but which I actually loved from the first sip: Jameson Irish Whiskey. Served on the rocks. I think I was out with my girlfriend and I just thought, "Why not?"

Jameson became my go-to drink until our honeymoon cruise. By then, I had tried some pretty decent mixed drinks, but I still couldn't stand wine or beer. The art auction on the cruise fixed that. It was the first time that I had ever had champagne. It was cheap, but it was actually pretty tasty. And it was free! Back home, I started trying other wines and found that I liked them.

I tried my first Guinness during our first year of marriage at my best friend from college's birthday party. I didn't even have to try to like it. It was just good. Rich, creamy, and delicious.

The common thread to all of these is that when I finally liked the drinks, I was having a good experience and the drink simply made it all the better. And that's the thing with taste. Our brain associates flavor with experience so that we have a revulsion to things that made us sick in the past (ever wonder why you sudden hate your favorite food after that one time you got food poisoning?).

tl;dr: It's possible to "hack" your brain by replacing negative flavor experiences with neutral or positive flavor experiences.