Can anyone please explain to me these lines by Paul in Dune Messiah?

Yes and what you prescience in real time is what gives the ability to obscure people, places and events. This idea was first introduced by Jesus in the Gospel of Thomas. I forgot the specific Logia, but the idea is before anything can happen, a consciousness must conceive it virginally in the mind, hence virgin birth / virgin creation. It is the first of its kind and only kind in its cubit of reality / time. Sexual creation is something everyone already knows. And he himself being virginally created, he was the first one of his kind and then thus the only one if anyone else achieves Christhood / Buddhahood, whatever version you wanna call it. The illusion is they are different and separate events, but they are the same.

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