Daily Ask Anything: 2018-03-12

SSRI and thyroid

You're a moron.

SSRI and Thyroid Article -

"Neither fluoxetine nor sertraline was associated with clinically significant changes in thyroid function or thyroid autoimmunity in either primary hypothyroid or normal thyroid function patients with depression. However, results suggest that patients with normal thyroid function who were treated with fluoxetine are more susceptible to minor changes within the serotoninergic system than patients with hypothyroidism on the same SSRI therapy. To the best of our knowledge, this is the first study to demonstrate the safety of administering SSRIs in hypothyroid patients."

As in euthyroid patients the changes are not so clear. And there have been clinical reports of Fluoxetine causing Hyperthyroidism.

  1. [Hyperthyroidism secondary to antidepressive treatment with fluoxetine] -- https://www.ncbi.nlm.nih.gov/pubmed/10638001

  2. Reversible Fluoxetine-Induced Hyperthyroidism: A Case Report -- https://www.ncbi.nlm.nih.gov/pubmed/26626429

  3. Hypothyroidism and hyperthyroidism in major depression revisited -- https://www.ncbi.nlm.nih.gov/pubmed/7737957

For the second comment, the link that you suggest also lists references. Reading the references:

Testosterone and depression: systematic review and meta-analysis -- https://www.ncbi.nlm.nih.gov/pubmed/19625884

They report that Test. Therapy had ANTI-depressing effects, ESPECIALLY those that have HYPOgonadism and Depression.

This beckons the questions of whether antidepressant drugs CAUSE low T. Or whether LOW T is a symptom of Depression? Or whether antidepressants FURTHER lower already decreased T levels.

Any more bullshit from you today?

/r/steroids Thread Parent