I enjoy resistance very very much.

I go to up to 3 game nights a week with different people.

One of them resistance is always the last game we play. With this group is very much a gamer's game. We all know all the plot cards, how many are left, and the best way to use them. We all know which spy is going to fail if there are multiple on the mission. With base rules of this group its often resistance weighted, so we play with a lot of variants, many of which will favor spies. With 9 players, for example. we almost always play with 4 spies instead of 3 (we'll counterbalance this someway as well -- 2 spy teams or something like that). We've made a lot of our 'own' variants. An Unknown that doesn't get to see their card, but gets to look at one other players card each mission. A group unknown where nobody gets to see their own card but it rotates each round and you get to see your card after it swaps. Variants for 2 groups where you change 1 person to the other group each round. Various ways of playing puppet master.
We enjoy resistance a lot and the variants make it a lot of fun.

With another game night I go to, I'll often bust it out if we have around 7/8 looking for a game at the same time. Usually we'll have at least one new player so I just play with plot cards and no unusual roles. IF they enjoy it, I'll introduce commander/assassin. If we end up playing with people who've all played before I'll bring out hunters/chiefs which is one of my favorite options the expansion added. A lot of people enjoy reversers and trapper is easy to add.

Sometimes I'll be in a situation where there is mostly NON-gamers and again resistance feels like a perfect game for this. Everyone participates during the whole game (As opposed to games where people have 'turns' ) and I found that non-gamers like this game more than any other gateway game I've tried.